Histochemistry and Tissue Processing Core Laboratory

Core Director: 
Heather Hardy

The Histochemistry and Tissue Processing Core Laboratory in Nemours Biomedical Research is a full-service histology laboratory located on the campus of the Nemours/Alfred I. duPont Hospital for Children in Wilmington, DE. In continuous operation since 1986, the Core Lab is CLIA-certified with two Histology Research Specialists and two Clinical Certified Specialists, HT (ASCP). The Lab has produced many posters and publications and also offers histology advisement for research project development. The Core serves both the research and clinical communities throughout Nemours.


  • Routine and special staining
  • Enzyme and immuno-histochemistry
  • Molecular histology
  • In situ hybridization/in situ PCR
  • Imaging and muscle histograms
  • Tissue micro - array
  • Cytology, cytospins and cell membrane staining
  • Antibody and probe development
  • Frozen, paraffin and plastic techniques
  • Consultations for research projects


  • (1) Array it - TMA
  • (1) HiTech imaging system with ImagePro Plus software
  • (3) Leica automated microtomes
  • (1) Leica Bond RX
  • (1) Leica cryostat
  • (1) Leica embedding center
  • (1) Leica processor
  • (1) Olympus Fluorescence microscope
  • (2) Olympus Light microsopes
  • (1) Sakura stainer
  • (1) Thermo Cryostat
  • (1) Thermo embedding center

Contact Information

Heather Hardy, HTL (ASCP)
302-651-6827 Office
302-651-6771 Laboratory
302-651-5010 FAX


  • Heather Hardy, Core Director, HTL (ASCP)
  • Brian Owens, Clinical Research Assistant I, HT (ASCP)
  • Bobbie Boyce, Histology Specialist III (Lead Tech)
  • Terry Kokas, Histology Specialist III
Departmental Unit: