Infections of Intrathecal Baclofen Delivery Systems and Ventriculoperitoneal Shunting Systems: Clinical Series Discussion

TitleInfections of Intrathecal Baclofen Delivery Systems and Ventriculoperitoneal Shunting Systems: Clinical Series Discussion
Publication TypeJournal Article
Year of Publication2018
AuthorsAbousamra, O., Duque Orozco M. D. P., Rogers K. J., Miller F., & Sees J. P.
JournalPediatric neurosurgery
Volume53
Issue1
Pagination1-6
Date Published2018
ISSN1423-0305
KeywordsAdolescent; Baclofen; Child; Child, Preschool; Equipment Contamination; Female; Humans; Infant; Infant, Newborn; Infection; Infusion Pumps, Implantable; Injections, Spinal; Intrathecal baclofen; Male; Muscle Relaxants, Central; Spasticity; Ventriculoperitoneal Shunt; Young Adult
Abstract

BACKGROUND/AIMS: The physiological interaction between the intrathecal baclofen (ITB) delivery system and the ventriculoperitoneal (VP) shunting system in a patient who had both systems implanted has not been reported previously. The aim of our report is to evaluate the effect that one system's infection might have on the other.
METHODS: Records of children who were followed at our institution between 2004 and 2015 for management of their ITB systems were reviewed. In this group, children who had VP shunts were identified, and those who had any of their ITB or VP systems infected were included.
RESULTS: Out of 313 children managed with ITB therapy at our institution, 31 (24%) children had VP shunts. Two patients had infection in both systems, and 3 patients had infection in 1 system.
CONCLUSION: This report suggests that if aspiration from both systems showed positive cultures, the treatment would be removal of both systems. If the primarily not infected system does not show positive cultures, it does not need to be removed. Close follow-up is recommended, and any sign of infection or malfunction of the primarily not infected device should be approached with a high level of suspicion.

DOI10.1159/000475468
Alternate JournalPediatr Neurosurg
Refereed DesignationRefereed