Use of magnetic resonance elastography to assess hepatic fibrosis in children with chronic liver disease

TitleUse of magnetic resonance elastography to assess hepatic fibrosis in children with chronic liver disease
Publication TypeJournal Article
Year of Publication2014
AuthorsXanthakos, S. A., Podberesky D. J., Serai S. D., Miles L., King E. C., Balistreri W. F., & Kohli R.
JournalThe Journal of pediatrics
Volume164
Issue1
Pagination186-8
Date Published2014 Jan
ISSN1097-6833
KeywordsAcoustic radiation force imaging; Adolescent; Area under the receiver operating characteristic curve; ARFI; AUROC; BMI; Body Mass Index; Child; Child, Preschool; Chronic Disease; Elasticity Imaging Techniques; Female; Humans; Liver Cirrhosis; Liver Diseases; Magnetic resonance elastography; Magnetic Resonance Imaging; Male; MRE; NAFLD; NASH; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Region of interest; Reproducibility of Results; Retrospective Studies; ROC Curve; ROI; Severity of Illness Index; TE; Transient elastography; Ultrasound; US; Young Adult
Abstract

Management of pediatric chronic liver disease is limited by lack of validated noninvasive biomarkers of histologic severity. We demonstrate that magnetic resonance elastography is feasible and accurate in detecting significant hepatic fibrosis in a case series of 35 children with chronic liver disease, including severely obese children.

DOI10.1016/j.jpeds.2013.07.050
Alternate JournalJ. Pediatr
Refereed DesignationRefereed