Continuous glucose monitoring in type 1 diabetes

TitleContinuous glucose monitoring in type 1 diabetes
Publication TypeJournal Article
Year of Publication2013
AuthorsMauras, N., Fox L., Englert K., & Beck R. W.
JournalEndocrine
Volume43
Issue1
Pagination41-50
Date Published2013 Feb
ISSN1559-0100
KeywordsAdolescent; Adult; Age Factors; Blood Glucose; Child, Preschool; Diabetes Mellitus, Type 1; Extracellular Fluid; Female; Humans; Hypoglycemic Agents; Insulin; Insulin Infusion Systems; Male; Monitoring, Ambulatory; Pregnancy; Pregnancy in Diabetics; Quality of Life
Abstract

Continuous glucose monitors (CGM), devices that can measure interstitial glucose in "real time," have become widely available particularly for use in patients with diabetes, and their accuracy and ease of use have greatly improved over the last decade. A number of large and well-controlled clinical trials have firmly established their usefulness in improving metabolic control (as measured by HbA1C) and decreasing time spent in hypoglycemia in adults; however, data have been less robust proving benefit in children and adolescents. Benefits are clearly linked to near-continuous wear. Insulin dosing algorithms based on CGM glucose trends have proven useful in dissecting the large volume of data generated daily by these devices, although these are imperfect tools, particularly in children. The technology is likely to be most useful when integrated with insulin pump delivery systems (sensor augmented). In this review, we concentrate on the analysis of published results of the largest trials in adults and children, including the very young, with diabetes.

DOI10.1007/s12020-012-9765-1
Alternate JournalEndocrine
Refereed DesignationRefereed